Ken Ruinard/Associated Press
Friday, Dec. 4
No. 25 Louisiana-Lafayette at Appalachian State (-2.5), 8:30 p.m. ET, ESPN
Saturday, Dec. 5
No. 4 Ohio State (-24) at Michigan State, noon ET, ABC
No. 5 Texas A&M (-7) at Auburn, noon ET, ESPN
No. 15 Oklahoma State (-2.5) at TCU, noon ET, ESPN2
Western Carolina at No. 17 North Carolina (-49.5), noon ET, ACC Network
Rice at No. 21 Marshall (-23.5), noon ET, ESPN+
Liberty at No. 18 Coastal Carolina (-10.5), 2 p.m. ET, ESPNU
Syracuse at No. 2 Notre Dame (-33.5), 2:30 p.m. ET, NBC
No. 6 Florida (-17.5) at Tennessee, 3:30 p.m. ET, CBS
West Virginia at No. 9 Iowa State (-6.5), 3:30 p.m. ET, ESPN
No. 12 Indiana at No. 16 Wisconsin (-14.5), 3:30 p.m. ET, ABC
No. 19 Iowa (-14) at Illinois, 3:30 p.m. ET, Fox Sports 1
No. 24 Tulsa (-12.5) at Navy, 3:30 p.m. ET, ESPN2
Vanderbilt at No. 8 Georgia (-35.5), 4 p.m. ET, SEC Network
Stanford at No. 22 Washington (-11.5), 4 p.m. ET, Fox
No. 23 Oregon (-9.5) at California, 7 p.m. ET, ESPN
No. 3 Clemson (-22.5) at Virginia Tech, 7:30 p.m. ET, ABC
No. 1 Alabama (-29.5) at LSU, 8 p.m. ET, CBS
No. 10 Miami (-14.5) at Duke, 8 p.m. ET, ACC Network
Baylor at No. 11 Oklahoma (-22.5), 8 p.m. ET, Fox
Sunday, Dec. 6
Washington State at No. 20 USC (-14.5), 7:30 p.m. ET, Fox Sports 1
Picks in bold against the spread. Odds via DraftKings.