Dosing ERROR at AstraZeneca-Oxford University vaccine trial led to huge boost in jab’s success rate

Dosing ERROR by researchers at the AstraZeneca-Oxford University vaccine trial led to huge boost in jab’s success rate, firm’s vice-president reveals

  • AstraZeneca scientist Mene Pangalos says ‘serendipity,’ led to a break through 
  • ‘Mistake’ helped scientists discover half-dose was more effective than a full one 
  • More analysis needed to explain why an initial lower dose was more effective

A dosing error by researchers on the AstraZeneca-Oxford University vaccine trial led to a huge boost in the jab’s success rate, the firm’s vice president has revealed.

Mene Pangalos, head of AstraZeneca’s non-oncology research and development, said: ‘The reason we had the half dose is serendipity.’

Volunteers in Britain were expected to receive two full doses of the vaccine as it was trialed in the hope of funding a cure.

Dr Pangalos says researches were

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How a 2015 Dolphins roster decision ultimately led to Emmanuel Ogbah’s career year

Call it the NFL’s version of the Butterfly Effect:

The Miami Dolphins — in choosing to low-ball Olivier Vernon when they could have signed him for relatively cheap, and then later refusing to pay him top dollar once his market exploded — set off a chain reaction that, five years later, resulted in Emmanuel Ogbah having the best season of his career … for the Miami Dolphins.

Convoluted? Yes.

But also accurate.

Here’s how:

After contract extension talks went nowhere for the better part of a year, the Dolphins in early 2016 let Vernon, a homegrown pass rusher, walk in free agency despite four productive years in Miami. Vernon, who attended the University of Miami, signed a five-year, $85 million contract with the Giants instead.

That same offseason, the Browns selected Ogbah, a defensive end from Oklahoma State, with the 32nd pick.

Both were fine with their new teams —

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Metagenomi closes USD 65 million Series A financing led by Leaps by Bayer and Humboldt Fund

• Metagenomi is a genomic medicines company pioneering precision gene editing systems to advance curative therapies for oncology and genetic diseases 
• Proprietary and wholly owned gene editing platform offers the potential to expand the range of treatable diseases and to improve patient access to cell and gene therapies

Metagenomi, a next generation gene editing company launched by UC Berkeley scientists in 2018, successfully completed a USD 65 million Series A financing round and emerged from stealth mode today. The Series A round was led by Leaps by Bayer and Humboldt Fund. Other investors included Sozo Ventures, Agent Capital, InCube Ventures and HOF Capital.

This press release features multimedia. View the full release here:

CRISPR-based gene editing is one of the most important discoveries in recent years, and a critical technology for next generation therapeutic development. With the ability to edit DNA, scientists can address a whole range of

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College Football Playoff race after Week 9 led by Alabama, Clemson


USA TODAY Sports’ Paul Myerberg breaks down the latest Amway Coaches Poll.


It’s taken Ohio State just two weeks to turn the race for the Big Ten championship into a mere formality.

The Buckeyes have put together easy wins against Nebraska (52-17) and Penn State (38-25) as quarterback Justin Fields has surged into prime Heisman Trophy contention.

Even the 13-point edge over the Nittany Lions, if impressive on its own, doesn’t do justice to the Buckeyes’ dominance of a projected Big Ten championship contender.

Combined with what’s happened elsewhere in the conference — namely Michigan’s stunning loss to rival Michigan State — this high level of play has Ohio State on a clear track for the College Football Playoff.

Ohio State wide receiver Garrett Wilson (5) runs past Nebraska safety Deontai Williams during the second half at Ohio Stadium. (Photo: Joseph Maiorana, USA TODAY Sports)

Typically released

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18 Trump rallies have led to 30,000 COVID-19 cases: Stanford University study

A new study from Stanford University found that 18 of President TrumpDonald John TrumpBiden leads Trump in survey of Texas voters from left-leaning pollster On The Trail: Making sense of Super Poll Sunday Trump rebukes FBI for investigating supporters accused of harassing Biden bus MORE’s campaign rallies have led to over 30,000 confirmed coronavirus cases and likely led to over 700 deaths. 

Researchers examined rallies held between June 20 and Sept. 22, 2020, only three of which were held indoors.

The researchers then compared spread of the virus in the counties that held the rallies to counties that were on similar case trajectories before the rallies occurred. 

The authors concluded that the rallies increased subsequent cases of COVID-19 by over 250 infections per 100,000 residents. They found that the events led to over 30,000 new cases in the country and likely resulted in over 700 deaths, but recognized

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College football midseason awards led by Ttrevor Lawrence, Mac Jones


USA TODAY Sports’ Paul Myerberg breaks down the latest Amway Coaches Poll.


Only in 2020 would college football’s midseason hit as one Power Five conference has played a single game and another league is more than a week away from kickoff.

While the Big Ten just got started and the Pac-12 won’t open until Nov. 7, the 2020 season began Sept. 5 and has heated up since the SEC opened on Sept. 26.

Despite the odd and mismatched schedules across Bowl Subdivision leagues, one aspect of the season has gone according to plan: Alabama and Clemson have carved out some distance from the rest of pack in the early College Football Playoff race.

Also predictable? That Clemson quarterback Trevor Lawrence would head into Halloween as the favorite for the Heisman.

As we reach the midway point, here’s a look at the players, teams, coaches and games that

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Chip Scale Package LED Market Research Report by Power Range, by Application – Global Forecast to 2025

Chip Scale Package LED Market Research Report by Power Range (High-Power and Low- & Mid-Power), by Application (Automotive Lighting, Backlighting Unit (BLU), Flash Lighting, and General Lighting) – Global Forecast to 2025 – Cumulative Impact of COVID-19

New York, Oct. 22, 2020 (GLOBE NEWSWIRE) — announces the release of the report “Chip Scale Package LED Market Research Report by Power Range, by Application – Global Forecast to 2025 – Cumulative Impact of COVID-19” –

The Global Chip Scale Package LED Market is expected to grow from USD 830.28 Million in 2019 to USD 2,015.16 Million by the end of 2025 at a Compound Annual Growth Rate (CAGR) of 15.92%.

Market Segmentation & Coverage:
This research report categorizes the Chip Scale Package LED to forecast the revenues and analyze the trends in each of the following sub-markets:

Based on Power Range, the Chip Scale Package LED Market studied across

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